Formulation of Chitosan Microparticles for Enhanced Intranasal Macromolecular Compound Delivery: Factors That Influence Particle Size during Ionic Gelation

Therapeutic macromolecules (e.g., protein and peptide drugs) present bioavailability challenges via extravascular administration. The nasal route presents an alternative non-invasive route for these drugs, although low bioavailability remains challenging. Co-administration of permeation enhancers is...

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Detalles Bibliográficos
Autores principales: Weyers, Morné, Peterson, Bianca, Hamman, Josias H., Steenekamp, Jan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689727/
https://www.ncbi.nlm.nih.gov/pubmed/36354594
http://dx.doi.org/10.3390/gels8110686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689727/
https://www.ncbi.nlm.nih.gov/pubmed/36354594
http://dx.doi.org/10.3390/gels8110686

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