Cargando…

Prx1 Regulates Thapsigargin-Mediated UPR Activation and Apoptosis

Endoplasmic reticulum (ER) stress activates the unfolded protein response (UPR) signaling via the accumulation of unfolded and misfolded proteins. ER stress leads to the production of reactive oxygen species (ROS), which are necessary to maintain redox homeostasis in the ER. Although peroxiredoxin 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eun-Kyung, Kim, Yosup, Yang, Jun Young, Jang, Ho Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689921/
https://www.ncbi.nlm.nih.gov/pubmed/36360274
http://dx.doi.org/10.3390/genes13112033