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Oridonin Protects against Myocardial Ischemia–Reperfusion Injury by Inhibiting GSDMD-Mediated Pyroptosis

Pyroptosis serves a crucial function in various types of ischemia and reperfusion injuries. Oridonin, a tetracycline diterpene derived from Rabdosia rubescens, can significantly inhibit the aggregation of NLRP3-mediated inflammasome. This experiment is aimed at investigating the effect of oridonin o...

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Detalles Bibliográficos
Autores principales: Lin, Jiahui, Lai, Xianhui, Fan, Xiaoxi, Ye, Bozhi, Zhong, Lingfeng, Zhang, Yucong, Shao, Ruiyin, Shi, Si, Huang, Weijian, Su, Lan, Ying, Miaomiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690185/
https://www.ncbi.nlm.nih.gov/pubmed/36421808
http://dx.doi.org/10.3390/genes13112133