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Polymorphism rs7079 in miR-31/-584 Binding Site in Angiotensinogen Gene Associates with Earlier Onset of Coronary Artery Disease in Central European Population

Angiotensinogen (AGT) represents a key component of the renin–angiotensin–aldosterone system (RAAS). Polymorphisms in the 3′ untranslated region (3′UTR) of the AGT gene may alter miRNA binding and cause disbalance in the RAAS. Within this study, we evaluated the possible association of AGT +11525C/A...

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Detalles Bibliográficos
Autores principales: Novák, Jan, Maceková, Soňa, Héžová, Renata, Máchal, Jan, Zlámal, Filip, Hlinomaz, Ota, Rezek, Michal, Souček, Miroslav, Vašků, Anna, Slabý, Ondřej, Bienertová-Vašků, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690213/
https://www.ncbi.nlm.nih.gov/pubmed/36360218
http://dx.doi.org/10.3390/genes13111981