Strategies for Bottlenecks of rAAV-Mediated Expression in Skeletal and Cardiac Muscle of Duchenne Muscular Dystrophy

Gene therapy using the adeno-associated virus (rAAV) to deliver mini/micro- dystrophin is the current promising strategy for Duchenne Muscular Dystrophy (DMD). However, the further transformation of this strategy still faces many “bottlenecks”. Most gene therapies are only suitable for infants with...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Na, Song, Yafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690237/
https://www.ncbi.nlm.nih.gov/pubmed/36360257
http://dx.doi.org/10.3390/genes13112021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690237/
https://www.ncbi.nlm.nih.gov/pubmed/36360257
http://dx.doi.org/10.3390/genes13112021

Ejemplares similares