Cargando…

SPOP in Cancer: Phenomena, Mechanisms and Its Role in Therapeutic Implications

Speckle-type POZ (pox virus and zinc finger protein) protein (SPOP) is a cullin 3-based E3 ubiquitin ligase adaptor protein that plays a crucial role in ubiquitin-mediated protein degradation. Recently, SPOP has attracted major research attention as it is frequently mutated in a range of cancers, hi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Xiaojuan, Zhu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690554/
https://www.ncbi.nlm.nih.gov/pubmed/36360288
http://dx.doi.org/10.3390/genes13112051