Evaluation of DNA Methylation Array for Glioma Tumor Profiling and Description of a Novel Epi-Signature to Distinguish IDH1/IDH2 Mutant and Wild-Type Tumors

Molecular biomarkers, such as IDH1/IDH2 mutations and 1p19q co-deletion, are included in the histopathological and clinical criteria currently used to diagnose and classify gliomas. IDH1/IDH2 mutation is a common feature of gliomas and is associated with a glioma-CpG island methylator phenotype (CIM...

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Detalles Bibliográficos
Autores principales: Schenkel, Laila C., Mathew, Joseph, Hirte, Hal, Provias, John, Paré, Guillaume, Chong, Michael, Grafodatskaya, Daria, McCready, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690723/
https://www.ncbi.nlm.nih.gov/pubmed/36360312
http://dx.doi.org/10.3390/genes13112075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690723/
https://www.ncbi.nlm.nih.gov/pubmed/36360312
http://dx.doi.org/10.3390/genes13112075

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