Cargando…

Seropositivity-Dependent Association between LINE-1 Methylation and Response to Methotrexate Therapy in Early Rheumatoid Arthritis Patients

Background: Methotrexate (MTX) is considered the first choice among disease-modifying anti-rheumatic drugs (DMARDs) for rheumatoid arthritis (RA) treatment. However, response to it varies as approximately 40% of the patients do not respond and would lose the most effective period of treatment time....

Descripción completa

Detalles Bibliográficos
Autores principales: Ravaei, Amin, Pulsatelli, Lia, Assirelli, Elisa, Meliconi, Riccardo, Ciaffi, Jacopo, Gremese, Elisa, Tolusso, Barbara, Salvarani, Carlo, Govoni, Marcello, Rubini, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690891/
https://www.ncbi.nlm.nih.gov/pubmed/36360249
http://dx.doi.org/10.3390/genes13112012