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Seropositivity-Dependent Association between LINE-1 Methylation and Response to Methotrexate Therapy in Early Rheumatoid Arthritis Patients

Background: Methotrexate (MTX) is considered the first choice among disease-modifying anti-rheumatic drugs (DMARDs) for rheumatoid arthritis (RA) treatment. However, response to it varies as approximately 40% of the patients do not respond and would lose the most effective period of treatment time....

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Detalles Bibliográficos
Autores principales:	Ravaei, Amin, Pulsatelli, Lia, Assirelli, Elisa, Meliconi, Riccardo, Ciaffi, Jacopo, Gremese, Elisa, Tolusso, Barbara, Salvarani, Carlo, Govoni, Marcello, Rubini, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9690891/ https://www.ncbi.nlm.nih.gov/pubmed/36360249 http://dx.doi.org/10.3390/genes13112012

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