Chalcogen Bond as a Factor Stabilizing Ligand Conformation in the Binding Pocket of Carbonic Anhydrase IX Receptor Mimic

It is postulated that the overexpression of Carbonic Anhydrase isozyme IX in some cancers contributes to the acidification of the extracellular matrix. It was proved that this promotes the growth and metastasis of the tumor. These observations have made Carbonic Anhydrase IX an attractive drug targe...

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Detalles Bibliográficos
Autores principales: Wojtkowiak, Kamil, Michalczyk, Mariusz, Zierkiewicz, Wiktor, Jezierska, Aneta, Panek, Jarosław J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691181/
https://www.ncbi.nlm.nih.gov/pubmed/36430173
http://dx.doi.org/10.3390/ijms232213701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691181/
https://www.ncbi.nlm.nih.gov/pubmed/36430173
http://dx.doi.org/10.3390/ijms232213701

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