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A functionalized self-assembling peptide containing E7 and YIGSR sequences enhances neuronal differentiation of spermatogonial stem cells on aligned PCL fibers for spinal cord injury repair

Background: Spinal cord injury (SCI) induces neuronal death and disrupts the nerve fiber bundles, which leads to partial or complete sensorimotor function loss of the limbs. Transplantation of exogenous neurons derived from stem cells to the lesion site becomes a new neurorestorative strategy for SC...

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Detalles Bibliográficos
Autores principales: Wang, Zhiyuan, Jia, Shuaijun, Xu, Hailiang, Wang, Xiaohui, Lu, Botao, Wu, Weidong, Huang, Dageng, Kong, Lingbo, Kang, Xin, Tian, Fang, Zhu, Lei, Hao, Dingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691349/
https://www.ncbi.nlm.nih.gov/pubmed/36438503
http://dx.doi.org/10.7150/thno.78448