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Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution

Rationale: The recurrence of cutaneous squamous cell carcinoma (cSCC) after surgery is associated with the reprogramming of the tumor microenvironment (TME), and remains a key factor affecting its outcomes. Methods: We employed single-cell RNA sequencing (scRNA-seq) to examine the dynamic changes in...

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Detalles Bibliográficos
Autores principales: Li, Xin, Zhao, Shuang, Bian, Xiaohui, Zhang, Lining, Lu, Lixia, Pei, Shiyao, Dong, Liang, Shi, Wensheng, Huang, Lingjuan, Zhang, Xiyuan, Chen, Mingliang, Chen, Xiang, Yin, Mingzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691356/
https://www.ncbi.nlm.nih.gov/pubmed/36438481
http://dx.doi.org/10.7150/thno.77528