Safety and Dosing Study of a Cholecystokinin Receptor Antagonist in Non‐alcoholic Steatohepatitis

High saturated fat diets have been shown to raise blood levels of cholecystokinin (CCK) and induce nonalcoholic steatohepatitis (NASH). CCK receptors are expressed on stellate cells and are responsible for hepatic fibrosis when activated. The purpose of this study was to test the safety and dose of...

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Detalles Bibliográficos
Autores principales: Rabiee, Atoosa, Gay, Martha D., Shivapurkar, Narayan, Cao, Hong, Nadella, Sandeep, Smith, Coleman I., Lewis, James H., Bansal, Sunil, Cheema, Amrita, Kwagyan, John, Smith, Jill P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691615/
https://www.ncbi.nlm.nih.gov/pubmed/36087237
http://dx.doi.org/10.1002/cpt.2745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691615/
https://www.ncbi.nlm.nih.gov/pubmed/36087237
http://dx.doi.org/10.1002/cpt.2745

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