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Single-dose of a replication-competent adenovirus-vectored vaccine provides sterilizing protection against Rift Valley fever virus challenge

Rift Valley fever virus (RVFV) is one of the most important virulent pathogens causing severe disease in animals and humans. However, there is currently no approved vaccine to prevent RVFV infection in humans. The use of human adenovirus serotype 4 (Ad4) as a vector for an RVFV vaccine has not been...

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Detalles Bibliográficos
Autores principales: Bian, Ting, Wang, Busen, Fu, Guangcheng, Hao, Meng, Chen, Yi, Fang, Ting, Liu, Shuling, Yu, Changming, Li, Jianmin, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691644/
https://www.ncbi.nlm.nih.gov/pubmed/36439179
http://dx.doi.org/10.3389/fimmu.2022.907675