Inhibition of the CD47-SIRPα axis for cancer therapy: A systematic review and meta-analysis of emerging clinical data

CD47-SIRPα interaction acts as a “don’t eat me” signal and is exploited by cancer to downregulate innate and adaptive immune surveillance. There has been intense interest to develop a mechanism of blockade, and we aimed to analyze the emerging data from early clinical trials. We performed a systemat...

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Detalles Bibliográficos
Autores principales: Son, Ji, Hsieh, Rodney Cheng-En, Lin, Heather Y., Krause, Kate J., Yuan, Ying, Biter, Amadeo B., Welsh, James, Curran, Michael A., Hong, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691650/
https://www.ncbi.nlm.nih.gov/pubmed/36439116
http://dx.doi.org/10.3389/fimmu.2022.1027235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691650/
https://www.ncbi.nlm.nih.gov/pubmed/36439116
http://dx.doi.org/10.3389/fimmu.2022.1027235

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