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Performance of the intracerebroventricularly injected streptozotocin Alzheimer’s disease model in a translationally relevant, aged and experienced rat population

The intracerebroventricularly (icv) injected streptozotocin (STZ) induced brain state is a widely used model of sporadic Alzheimer-disease (AD). However, data have been generated in young, naive albino rats. We postulate that the translationally most relevant animal population of an AD model should...

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Detalles Bibliográficos
Autores principales: Gáspár, Attila, Hutka, Barbara, Ernyey, Aliz Judit, Tajti, Brigitta Tekla, Varga, Bence Tamás, Zádori, Zoltán Sándor, Gyertyán, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691696/
https://www.ncbi.nlm.nih.gov/pubmed/36424423
http://dx.doi.org/10.1038/s41598-022-24292-5