Type I interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia

Macrophages are key target cells of Zika virus (ZIKV) infection, implicated as a viral reservoir seeding sanctuary sites such as the central nervous system and testes. This rests on the apparent ability of macrophages to sustain ZIKV replication without experiencing cytopathic effects. ZIKV infectio...

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Detalles Bibliográficos
Autores principales: Hanrath, Aidan T., Hatton, Catherine F., Gothe, Florian, Browne, Cathy, Vowles, Jane, Leary, Peter, Cockell, Simon J., Cowley, Sally A., James, William S., Hambleton, Sophie, Duncan, Christopher J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691778/
https://www.ncbi.nlm.nih.gov/pubmed/36439115
http://dx.doi.org/10.3389/fimmu.2022.1035532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691778/
https://www.ncbi.nlm.nih.gov/pubmed/36439115
http://dx.doi.org/10.3389/fimmu.2022.1035532

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