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X-box binding protein 1: A new metabolic mediator and drug target of metformin?

Accumulating evidence has demonstrated that metformin improved hypertriglyceridemia. The present study aim to investigate the molecular mechanism by which metformin improves hypertriglyceridemia via regulation of diacylglycerol O-acyltransferase 2 (DGAT2) and X-box binding protein 1 (XBP1) in the li...

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Detalles Bibliográficos
Autores principales: Lou, Kai, Sun, Pei, Zhang, Chunxue, Jiang, Qiang, Pang, Shuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691898/
https://www.ncbi.nlm.nih.gov/pubmed/36438823
http://dx.doi.org/10.3389/fphar.2022.1013218