Single dose topical inserts containing tenofovir alafenamide fumarate and elvitegravir provide pre- and post-exposure protection against vaginal SHIV infection in macaques

BACKGROUND: Vaginal products for HIV prevention that can be used on-demand before or after sex may be a preferable option for women with low frequency or unplanned sexual activity or who prefer not to use daily or long-acting pre-exposure prophylaxis (PrEP). We performed dose ranging pharmacokinetic...

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Detalles Bibliográficos
Autores principales: Dobard, Charles W., Peet, M. Melissa, Nishiura, Kenji, Holder, Angela, Dinh, Chuong, Mitchell, James, Khalil, George, Pan, Yi, Singh, Onkar N., McCormick, Timothy J., Agrahari, Vivek, Gupta, Pardeep, Jonnalagadda, Sriramakamal, Heneine, Walid, Clark, Meredith R., García-Lerma, J. Gerardo, Doncel, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691909/
https://www.ncbi.nlm.nih.gov/pubmed/36423375
http://dx.doi.org/10.1016/j.ebiom.2022.104361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691909/
https://www.ncbi.nlm.nih.gov/pubmed/36423375
http://dx.doi.org/10.1016/j.ebiom.2022.104361

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