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Characterization of genomic alterations and neoantigens and analysis of immune infiltration identified therapeutic and prognostic biomarkers in adenocarcinoma at the gastroesophageal junction

OBJECTIVES: Adenocarcinoma at the gastroesophageal junction (ACGEJ) refers to a malignant tumor that occurs at the esophagogastric junction. Despite some progress in targeted therapies for HER2, FGFR2, EGFR, MET, Claudin 18.2 and immune checkpoints in ACGEJ tumors, the 5-year survival rate of patien...

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Detalles Bibliográficos
Autores principales: Lao, Yueqiong, Wang, Yuqian, Yang, Jie, Liu, Tianyuan, Ma, Yuling, Luo, Yingying, Sun, Yanxia, Li, Kai, Zhao, Xuan, Niu, Xiangjie, Xi, Yiyi, Zhong, Ce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691957/
https://www.ncbi.nlm.nih.gov/pubmed/36439494
http://dx.doi.org/10.3389/fonc.2022.941868