Integrating RNA-seq and scRNA-seq to explore the biological significance of NAD + metabolism-related genes in the initial diagnosis and relapse of childhood B-cell acute lymphoblastic leukemia

BACKGROUND: Nicotinamide Adenine Dinucleotide (NAD) depletion is reported to be a potential treatment for B-cell Acute Lymphoblastic Leukemia (B-ALL), but the mechanism of NAD metabolism-related genes (NMRGs) in B-ALL relapse remains unclear. METHODS: Transcriptome data (GSE3912), and single-cell se...

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Detalles Bibliográficos
Autores principales: Lin, Chao, Xu, Jia-Qi, Zhong, Gui-Chao, Chen, Hui, Xue, Hong-Man, Yang, Mo, Chen, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691973/
https://www.ncbi.nlm.nih.gov/pubmed/36439178
http://dx.doi.org/10.3389/fimmu.2022.1043111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691973/
https://www.ncbi.nlm.nih.gov/pubmed/36439178
http://dx.doi.org/10.3389/fimmu.2022.1043111

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