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Methylation-based reclassification and risk stratification of skull-base chordomas
BACKGROUND: Skull-base chordomas are rare malignant bone cancers originating from the remnant of the notochord. Survival is variable, and clinical or molecular factors cannot reliably predict their outcomes. This study therefore identified epigenetic subtypes that defined new chordoma epigenetic pro...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691996/ https://www.ncbi.nlm.nih.gov/pubmed/36439461 http://dx.doi.org/10.3389/fonc.2022.960005 |