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Methylation-based reclassification and risk stratification of skull-base chordomas

BACKGROUND: Skull-base chordomas are rare malignant bone cancers originating from the remnant of the notochord. Survival is variable, and clinical or molecular factors cannot reliably predict their outcomes. This study therefore identified epigenetic subtypes that defined new chordoma epigenetic pro...

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Detalles Bibliográficos
Autores principales: Huo, Xulei, Guo, Tengxian, Wang, Ke, Yao, Bohan, Li, Da, Li, Huan, Chen, Wei, Wang, Liang, Wu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691996/
https://www.ncbi.nlm.nih.gov/pubmed/36439461
http://dx.doi.org/10.3389/fonc.2022.960005