A high throughput proliferation and cytotoxicity assay for co-cultured isogenic cell lines

PTEN is a well-known tumor suppressor that is inactivated or suppressed at a high frequency in cancer. We sought an assay to screen compounds for ones that differentially inhibited proliferation or induced cytotoxicity in PTEN mutated cancer cells. We employed the isogenic pair of cell lines MCF10-A...

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Detalles Bibliográficos
Autores principales: Ahmad, Syed, Wood, Kris C., Scott, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692025/
https://www.ncbi.nlm.nih.gov/pubmed/36438856
http://dx.doi.org/10.1016/j.mex.2022.101927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692025/
https://www.ncbi.nlm.nih.gov/pubmed/36438856
http://dx.doi.org/10.1016/j.mex.2022.101927

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