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Implication of platelets and complement C3 as link between innate immunity and tubulointerstitial injury in renal vasculitis with MPO-ANCA seropositivity

INTRODUCTION: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a potentially life-threatening systemic small-vessel vasculitis that is characterized by pauci-immune glomerulonephritis, depicting in turn a major denominator of AAV mortality. It is well established that AAV pa...

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Detalles Bibliográficos
Autores principales: Baier, Eva, Tampe, Désirée, Kluge, Ingmar Alexander, Hakroush, Samy, Tampe, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692128/
https://www.ncbi.nlm.nih.gov/pubmed/36439156
http://dx.doi.org/10.3389/fimmu.2022.1054457