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Creation of a new Drosophila melanogaster X chromosome balancer, First Multiple 8 ( FM8 ), using the CRISPR/Cas9 gene-editing system

Balancer chromosomes contain multiple inversions that work to suppress crossing over and prevent recovery of most recombinant chromosomes, allowing for alleles to be kept long-term without selection. These balancers are incredible tools, but some alleles within larger inverted segments are still los...

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Detalles Bibliográficos
Autores principales: Muron, Savannah, Kucera, Steve, Oliver, Brian, Benner, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692231/
https://www.ncbi.nlm.nih.gov/pubmed/36439394
http://dx.doi.org/10.17912/micropub.biology.000663