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Creation of a new Drosophila melanogaster X chromosome balancer, First Multiple 8 ( FM8 ), using the CRISPR/Cas9 gene-editing system
Balancer chromosomes contain multiple inversions that work to suppress crossing over and prevent recovery of most recombinant chromosomes, allowing for alleles to be kept long-term without selection. These balancers are incredible tools, but some alleles within larger inverted segments are still los...
Autores principales: | Muron, Savannah, Kucera, Steve, Oliver, Brian, Benner, Leif |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Caltech Library
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692231/ https://www.ncbi.nlm.nih.gov/pubmed/36439394 http://dx.doi.org/10.17912/micropub.biology.000663 |
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