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High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lymphoma

NK/T-cell lymphoma (NKTCL) and γδ T-cell non-Hodgkin lymphomas (γδ T-NHL) are highly aggressive lymphomas that lack rationally designed therapies and rely on repurposed chemotherapeutics from other hematological cancers. Histone deacetylases (HDACs) have been targeted in a range of malignancies, inc...

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Detalles Bibliográficos
Autores principales: Garcha, Harsimran Kaur, Nawar, Nabanita, Sorger, Helena, Erdogan, Fettah, Aung, Myint Myat Khine, Sedighi, Abootaleb, Manaswiyoungkul, Pimyupa, Seo, Hyuk-Soo, Schönefeldt, Susann, Pölöske, Daniel, Dhe-Paganon, Sirano, Neubauer, Heidi A., Mustjoki, Satu M., Herling, Marco, de Araujo, Elvin D., Moriggl, Richard, Gunning, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692247/
https://www.ncbi.nlm.nih.gov/pubmed/36355493
http://dx.doi.org/10.3390/ph15111321