A Microfluidic Approach for Probing Heterogeneity in Cytotoxic T-Cells by Cell Pairing in Hydrogel Droplets

Cytotoxic T-cells (CTLs) exhibit strong effector functions to leverage antigen-specific anti-tumoral and anti-viral immunity. When naïve CTLs are activated by antigen-presenting cells (APCs) they display various levels of functional heterogeneity. To investigate this, we developed a single-cell drop...

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Detalles Bibliográficos
Autores principales: Tiemeijer, Bart M., Descamps, Lucie, Hulleman, Jesse, Sleeboom, Jelle J. F., Tel, Jurjen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692327/
https://www.ncbi.nlm.nih.gov/pubmed/36363930
http://dx.doi.org/10.3390/mi13111910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692327/
https://www.ncbi.nlm.nih.gov/pubmed/36363930
http://dx.doi.org/10.3390/mi13111910

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