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A Microfluidic Approach for Probing Heterogeneity in Cytotoxic T-Cells by Cell Pairing in Hydrogel Droplets
Cytotoxic T-cells (CTLs) exhibit strong effector functions to leverage antigen-specific anti-tumoral and anti-viral immunity. When naïve CTLs are activated by antigen-presenting cells (APCs) they display various levels of functional heterogeneity. To investigate this, we developed a single-cell drop...
Autores principales: | Tiemeijer, Bart M., Descamps, Lucie, Hulleman, Jesse, Sleeboom, Jelle J. F., Tel, Jurjen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692327/ https://www.ncbi.nlm.nih.gov/pubmed/36363930 http://dx.doi.org/10.3390/mi13111910 |
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