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Polyphosphate Activates von Willebrand Factor Interaction with Glycoprotein Ib in the Absence of Factor VIII In Vitro

Polyphosphate (polyP), a phosphate polymer released by activated platelets, may modulate various stages of hemostasis by binding to blood proteins. In this context, we previously reported that polyP binds to the von Willebrand factor (VWF). One of the most significant functions of VWF is to bind to...

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Detalles Bibliográficos
Autores principales: Montilla, Marcela, Atienza-Navarro, Isabel, García-Cozar, Francisco Jose, Castro, Carmen, Rodríguez-Martorell, Francisco Javier, Ruiz, Felix A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692336/
https://www.ncbi.nlm.nih.gov/pubmed/36430595
http://dx.doi.org/10.3390/ijms232214118