Therapeutic Effect of Polymeric Nanomicelles Formulation of LY2157299-Galunisertib on CCl(4)-Induced Liver Fibrosis in Rats

Hepatic fibrosis (HF) is a major cause of liver-related disorders and together with cancer-associated fibroblasts can favor liver cancer development by modulating the tumor microenvironment. Advanced HF, characterized by an excess of extracellular matrix (ECM), is mediated by TGF- β1, that activates...

Descripción completa

Detalles Bibliográficos
Autores principales: Panzarini, Elisa, Leporatti, Stefano, Tenuzzo, Bernardetta Anna, Quarta, Alessandra, Hanafy, Nemany A. N., Giannelli, Gianluigi, Moliterni, Camilla, Vardanyan, Diana, Sbarigia, Carolina, Fidaleo, Marco, Tacconi, Stefano, Dini, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692463/
https://www.ncbi.nlm.nih.gov/pubmed/36579532
http://dx.doi.org/10.3390/jpm12111812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692463/
https://www.ncbi.nlm.nih.gov/pubmed/36579532
http://dx.doi.org/10.3390/jpm12111812

Ejemplares similares