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Therapeutic Effect of Polymeric Nanomicelles Formulation of LY2157299-Galunisertib on CCl(4)-Induced Liver Fibrosis in Rats
Hepatic fibrosis (HF) is a major cause of liver-related disorders and together with cancer-associated fibroblasts can favor liver cancer development by modulating the tumor microenvironment. Advanced HF, characterized by an excess of extracellular matrix (ECM), is mediated by TGF- β1, that activates...
Autores principales: | Panzarini, Elisa, Leporatti, Stefano, Tenuzzo, Bernardetta Anna, Quarta, Alessandra, Hanafy, Nemany A. N., Giannelli, Gianluigi, Moliterni, Camilla, Vardanyan, Diana, Sbarigia, Carolina, Fidaleo, Marco, Tacconi, Stefano, Dini, Luciana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692463/ https://www.ncbi.nlm.nih.gov/pubmed/36579532 http://dx.doi.org/10.3390/jpm12111812 |
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