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Multiparametric Magnetic Resonance Imaging and Metabolic Characterization of Patient-Derived Xenograft Models of Clear Cell Renal Cell Carcinoma

Patient-derived xenografts (PDX) are high-fidelity cancer models typically credentialled by genomics, transcriptomics and proteomics. Characterization of metabolic reprogramming, a hallmark of cancer, is less frequent. Dysregulated metabolism is a key feature of clear cell renal cell carcinoma (ccRC...

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Detalles Bibliográficos
Autores principales: Agudelo, Joao Piraquive, Upadhyay, Deepti, Zhang, Dalin, Zhao, Hongjuan, Nolley, Rosalie, Sun, Jinny, Agarwal, Shubhangi, Bok, Robert A., Vigneron, Daniel B., Brooks, James D., Kurhanewicz, John, Peehl, Donna M., Sriram, Renuka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692472/
https://www.ncbi.nlm.nih.gov/pubmed/36422257
http://dx.doi.org/10.3390/metabo12111117