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NEAT1 Confers Radioresistance to Hepatocellular Carcinoma Cells by Inducing PINK1/Parkin-Mediated Mitophagy

A long noncoding RNA, nuclear paraspeckle assembly transcript 1 (NEAT1) variant 1 (NEAT1v1), confers radioresistance to hepatocellular carcinoma (HCC) cells by inducing autophagy via γ-aminobutyric acid A receptor-associated protein (GABARAP). Radiation induces oxidative stress to damage cellular co...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Hiroyuki, Shinonaga, Ririko, Sakaguchi, Hiromi, Kitagawa, Yutaka, Yoshida, Kenji, Shiota, Goshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692527/
https://www.ncbi.nlm.nih.gov/pubmed/36430876
http://dx.doi.org/10.3390/ijms232214397