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TREML2 Gene Expression and Its Missense Variant rs3747742 Associate with White Matter Hyperintensity Volume and Alzheimer’s Disease-Related Brain Atrophy in the General Population

Although the common pathology of Alzheimer’s disease (AD) and white matter hyperintensities (WMH) is disputed, the gene TREML2 has been implicated in both conditions: its whole-blood gene expression was associated with WMH volume and its missense variant rs3747742 with AD risk. We re-examined those...

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Detalles Bibliográficos
Autores principales: Kühn, Annemarie Luise, Frenzel, Stefan, Teumer, Alexander, Wittfeld, Katharina, Garvert, Linda, Weihs, Antoine, Homuth, Georg, Prokisch, Holger, Bülow, Robin, Nauck, Matthias, Völker, Uwe, Völzke, Henry, Grabe, Hans Jörgen, Van der Auwera, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692564/
https://www.ncbi.nlm.nih.gov/pubmed/36430248
http://dx.doi.org/10.3390/ijms232213764