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Structural Basis of Parasitic HSP90 ATPase Inhibition by Small Molecules

Protozoan parasites are responsible for several harmful and widespread human diseases that cause high morbidity and mortality. Currently available treatments have serious limitations due to poor efficiency, strong adverse effects, and high cost. Hence, the identification of new targets and the devel...

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Detalles Bibliográficos
Autores principales: Tassone, Giusy, Mazzorana, Marco, Pozzi, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692773/
https://www.ncbi.nlm.nih.gov/pubmed/36355513
http://dx.doi.org/10.3390/ph15111341