A β-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells

Synthetic double-stranded small interfering RNAs (siRNAs) mimic interference RNAs (RNAi) and can bind target mRNAs with a high degree of specificity, leading to selective knockdown of the proteins they encode. However, siRNAs are very labile and must be both protected and transported by nanoparticle...

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Detalles Bibliográficos
Autores principales: de la Torre, Cristina, Játiva, Pablo, Posadas, Inmaculada, Manzanares, Darío, Blanco, José L. Jiménez, Mellet, Carmen Ortiz, Fernández, José Manuel García, Ceña, Valentín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692777/
https://www.ncbi.nlm.nih.gov/pubmed/36365241
http://dx.doi.org/10.3390/pharmaceutics14112424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692777/
https://www.ncbi.nlm.nih.gov/pubmed/36365241
http://dx.doi.org/10.3390/pharmaceutics14112424

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