Molecular Dynamics Simulation of Drug Solubilization Behavior in Surfactant and Cosolvent Injections

Surfactants and cosolvents are often combined to solubilize insoluble drugs in commercially available intravenous formulations to achieve better solubilization. In this study, six marketed parenteral formulations with surfactants and cosolvents were investigated on the aggregation processes of micel...

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Detalles Bibliográficos
Autores principales: He, Meiqi, Zheng, Wenwen, Wang, Nannan, Gao, Hanlu, Ouyang, Defang, Huang, Zunnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692798/
https://www.ncbi.nlm.nih.gov/pubmed/36365184
http://dx.doi.org/10.3390/pharmaceutics14112366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692798/
https://www.ncbi.nlm.nih.gov/pubmed/36365184
http://dx.doi.org/10.3390/pharmaceutics14112366

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