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The Histamine H(4) Receptor Participates in the Neuropathic Pain-Relieving Activity of the Histamine H(3) Receptor Antagonist GSK189254

Growing evidence points to the histamine system as a promising target for the management of neuropathic pain. Preclinical studies reported the efficacy of H(3)R antagonists in reducing pain hypersensitivity in models of neuropathic pain through an increase of histamine release within the CNS. Recent...

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Detalles Bibliográficos
Autores principales: Borgonetti, Vittoria, Galeotti, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692811/
https://www.ncbi.nlm.nih.gov/pubmed/36430790
http://dx.doi.org/10.3390/ijms232214314