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The Histamine H(4) Receptor Participates in the Neuropathic Pain-Relieving Activity of the Histamine H(3) Receptor Antagonist GSK189254
Growing evidence points to the histamine system as a promising target for the management of neuropathic pain. Preclinical studies reported the efficacy of H(3)R antagonists in reducing pain hypersensitivity in models of neuropathic pain through an increase of histamine release within the CNS. Recent...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692811/ https://www.ncbi.nlm.nih.gov/pubmed/36430790 http://dx.doi.org/10.3390/ijms232214314 |