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Characterization of the Secreted Acid Phosphatase SapS Reveals a Novel Virulence Factor of Staphylococcus aureus That Contributes to Survival and Virulence in Mice

Staphylococcus aureus possesses a large arsenal of immune-modulating factors, enabling it to bypass the immune system’s response. Here, we demonstrate that the acid phosphatase SapS is secreted during macrophage infection and promotes its intracellular survival in this type of immune cell. In animal...

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Detalles Bibliográficos
Autores principales: Ahmad-Mansour, Nour, Elhawy, Mohamed Ibrahem, Huc-Brandt, Sylvaine, Youssouf, Nadhuma, Pätzold, Linda, Martin, Marianne, Abdel-Wadood, Noran, Aljohmani, Ahmad, Morsli, Madjid, Krasteva-Christ, Gabriela, Becker, Sören L., Yildiz, Daniela, Lavigne, Jean-Philippe, Gannoun-Zaki, Laila, Bischoff, Markus, Molle, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692844/
https://www.ncbi.nlm.nih.gov/pubmed/36430506
http://dx.doi.org/10.3390/ijms232214031