MT1-MMP Expression Levels and Catalytic Functions Dictate LDL Receptor-Related Protein-1 Ligand Internalization Capacity in U87 Glioblastoma Cells

Modulations in cell surface receptor ectodomain proteolytic shedding impact on receptor function and cancer biomarker expression. As such, heavily pursued therapeutic avenues have exploited LDL receptor-related protein-1 (LRP-1)-mediated capacity in internalizing Angiopep-2 (An2), a brain-penetratin...

Descripción completa

Detalles Bibliográficos
Autores principales: Pratt, Jonathan, Haidara, Khadidja, Annabi, Borhane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692856/
https://www.ncbi.nlm.nih.gov/pubmed/36430705
http://dx.doi.org/10.3390/ijms232214214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692856/
https://www.ncbi.nlm.nih.gov/pubmed/36430705
http://dx.doi.org/10.3390/ijms232214214

Ejemplares similares