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Gαq Is the Specific Mediator of PAR-1 Transactivation of Kinase Receptors in Vascular Smooth Muscle Cells

Aims: G protein-coupled receptor (GPCR) transactivation of kinase receptors greatly expands the actions attributable to GPCRs. Thrombin, via its cognate GPCR, protease-activated receptor (PAR)-1, transactivates tyrosine and serine/threonine kinase receptors, specifically the epidermal growth factor...

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Detalles Bibliográficos
Autores principales: Kamato, Danielle, Gabr, Mai, Kumarapperuma, Hirushi, Chia, Zheng J., Zheng, Wenhua, Xu, Suowen, Osman, Narin, Little, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692893/
https://www.ncbi.nlm.nih.gov/pubmed/36430902
http://dx.doi.org/10.3390/ijms232214425