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G-Quadruplex DNA and Other Non-Canonical B-Form DNA Motifs Influence Productive and Latent HIV-1 Integration and Reactivation Potential

The integration of the HIV-1 genome into the host genome is an essential step in the life cycle of the virus and it plays a critical role in the expression, long-term persistence, and reactivation of HIV expression. To better understand the local genomic environment surrounding HIV-1 proviruses, we...

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Detalles Bibliográficos
Autores principales: Ajoge, Hannah O., Kohio, Hinissan P., Paparisto, Ermela, Coleman, Macon D., Wong, Kemen, Tom, Sean K., Bain, Katie L., Berry, Charles C., Arts, Eric J., Barr, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692945/
https://www.ncbi.nlm.nih.gov/pubmed/36423103
http://dx.doi.org/10.3390/v14112494