Cargando…

Discovery of New Glucose Uptake Inhibitors as Potential Anticancer Agents by Non-Radioactive Cell-Based Assays

Tumor cells rely on aerobic glycolysis to support growth and survival, thus require more glucose supply. Glucose transporters GLUTs, primarily GLUT1, are overexpressed in various cancers. Targeting GLUTs has been regarded as a promising anticancer strategy. In this study, we first evaluated 75 poten...

Descripción completa

Detalles Bibliográficos
Autores principales: Hung, Hsueh-Chih, Li, Li-Cheng, Guh, Jih-Hwa, Kung, Fan-Lu, Hsu, Lih-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692963/
https://www.ncbi.nlm.nih.gov/pubmed/36432207
http://dx.doi.org/10.3390/molecules27228106