Structure and Catalytic Mechanism of Radical SAM Methylases

Methyl transfer is essential in myriad biological pathways found across all domains of life. Unlike conventional methyltransferases that catalyze this reaction through nucleophilic substitution, many members of the radical S-adenosyl-L-methionine (SAM) enzyme superfamily use radical-based chemistry...

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Detalles Bibliográficos
Autores principales: Nguyen, Tu-Quynh, Nicolet, Yvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692996/
https://www.ncbi.nlm.nih.gov/pubmed/36362886
http://dx.doi.org/10.3390/life12111732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9692996/
https://www.ncbi.nlm.nih.gov/pubmed/36362886
http://dx.doi.org/10.3390/life12111732

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