Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as β-Glucuronidase Inhibitors: In Vitro and In Silico Studies

Currently the discovery and development of potent β-glucuronidase inhibitors is an active area of research due to the observation that increased activity of this enzyme is associated with many pathological conditions, such as colon cancer, renal diseases, and infections of the urinary tract. In this...

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Detalles Bibliográficos
Autores principales: Iqbal, Sarosh, Shaikh, Nimra Naveed, Khan, Khalid Mohammed, Kiran, Shumaila, Naz, Sehrish, Ul-Haq, Zaheer, Perveen, Shahnaz, Choudhary, M. Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693052/
https://www.ncbi.nlm.nih.gov/pubmed/36431887
http://dx.doi.org/10.3390/molecules27227786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693052/
https://www.ncbi.nlm.nih.gov/pubmed/36431887
http://dx.doi.org/10.3390/molecules27227786

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