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Pre-Existing HSV-1 Immunity Enhances Anticancer Efficacy of a Novel Immune-Stimulating Oncolytic Virus

Oncolytic viruses (OVs) can specifically replicate in the host and cause cancer cell lysis while inducing an antitumor immune response. The aim of this study is to investigate the impact of either pre-existing immunity against herpes simplex virus type-1 (HSV-1) or multicycle treatment with OVs on a...

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Detalles Bibliográficos
Autores principales: Ding, Jun, Murad, Yanal M., Sun, Yi, Lee, I-Fang, Samudio, Ismael, Liu, Xiaohu, Jia, William Wei-Guo, Zhao, Ronghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693100/
https://www.ncbi.nlm.nih.gov/pubmed/36366425
http://dx.doi.org/10.3390/v14112327