Protective Effect of Flavonoids against Methylglyoxal-Induced Oxidative Stress in PC-12 Neuroblastoma Cells and Its Structure–Activity Relationships

Methylglyoxal-induced oxidative stress and cytotoxicity are the main factors causing neuronal death-related, diabetically induced memory impairment. Antioxidant and anti-apoptotic therapy are potential intervention strategies. In this study, 25 flavonoids with different substructures were assayed fo...

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Detalles Bibliográficos
Autores principales: Zhang, Danyang, Li, Xia, He, Xiaoshi, Xing, Yan, Jiang, Bo, Xiu, Zhilong, Bao, Yongming, Dong, Yuesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693184/
https://www.ncbi.nlm.nih.gov/pubmed/36431904
http://dx.doi.org/10.3390/molecules27227804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693184/
https://www.ncbi.nlm.nih.gov/pubmed/36431904
http://dx.doi.org/10.3390/molecules27227804

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