Cargando…

Protective Effect of Flavonoids against Methylglyoxal-Induced Oxidative Stress in PC-12 Neuroblastoma Cells and Its Structure–Activity Relationships

Methylglyoxal-induced oxidative stress and cytotoxicity are the main factors causing neuronal death-related, diabetically induced memory impairment. Antioxidant and anti-apoptotic therapy are potential intervention strategies. In this study, 25 flavonoids with different substructures were assayed fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Danyang, Li, Xia, He, Xiaoshi, Xing, Yan, Jiang, Bo, Xiu, Zhilong, Bao, Yongming, Dong, Yuesheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693184/ https://www.ncbi.nlm.nih.gov/pubmed/36431904 http://dx.doi.org/10.3390/molecules27227804

Ejemplares similares

Flavonoids of Kudzu Root Fermented by Eurtotium cristatum Protected Rat Pheochromocytoma Line 12 (PC12) Cells against H(2)O(2)-Induced Apoptosis
por: Zhang, Bo, et al.
Publicado: (2017)

Resveratrol Protects Mouse Oocytes from Methylglyoxal-Induced Oxidative Damage
por: Liu, Yu, et al.
Publicado: (2013)

Protective Effect of Quercetin against Oxidative Stress-Induced Cytotoxicity in Rat Pheochromocytoma (PC-12) Cells
por: Bao, Dengke, et al.
Publicado: (2017)

Dendrobium officinale Polysaccharide Prevents Diabetes via the Regulation of Gut Microbiota in Prediabetic Mice
por: Liu, Haodong, et al.
Publicado: (2023)

Antioxidant potential, total phenolic and total flavonoid contents of Rhododendron anthopogonoides and its protective effect on hypoxia-induced injury in PC12 cells
por: Jing, Linlin, et al.
Publicado: (2015)

Methylglyoxal Scavengers Attenuate Angiogenesis Dysfunction Induced by Methylglyoxal and Oxygen-Glucose Deprivation
por: Chen, Wei, et al.
Publicado: (2022)

Didymin: an orally active citrus flavonoid for targeting neuroblastoma
por: Singhal, Sharad S., et al.
Publicado: (2017)

Luteolin, a natural flavonoid, inhibits methylglyoxal induced apoptosis via the mTOR/4E-BP1 signaling pathway
por: Liu, Yi, et al.
Publicado: (2017)

Resveratrol Protects against Methylglyoxal-Induced Hyperglycemia and Pancreatic Damage In Vivo
por: Cheng, An-Sheng, et al.
Publicado: (2015)

Pharmacological Potentiality of Bioactive Flavonoid against Ketamine Induced Cell Death of PC 12 Cell Lines: An In Vitro Study
por: Venkataramaiah, Chintha, et al.
Publicado: (2021)

Taurine protection of PC12 cells against endoplasmic reticulum stress induced by oxidative stress
por: Pan, Chunliu, et al.
Publicado: (2010)

The Timing of Raf/ERK and AKT Activation in Protecting PC12 Cells against Oxidative Stress
por: Ong, Qunxiang, et al.
Publicado: (2016)

Methylglyoxal metabolism in trypanosomes and leishmania
por: Wyllie, Susan, et al.
Publicado: (2011)

Role of Methylglyoxal in Alzheimer's Disease
por: Angeloni, Cristina, et al.
Publicado: (2014)

Methylglyoxal, the dark side of glycolysis
por: Allaman, Igor, et al.
Publicado: (2015)

Interplay among Oxidative Stress, Methylglyoxal Pathway and S-Glutathionylation
por: de Bari, Lidia, et al.
Publicado: (2020)

Sulforaphane prevents PC12 cells from oxidative damage via the Nrf2 pathway
por: Bao, Bing, et al.
Publicado: (2019)

A New Saponin from Tea Seed Pomace (Camellia oleifera Abel) and Its Protective Effect on PC12 Cells
por: Zhang, Xin-Fu, et al.
Publicado: (2012)

Melatonin Analogues Potently Inhibit MAO-B and Protect PC12 Cells against Oxidative Stress
por: Elkamhawy, Ahmed, et al.
Publicado: (2021)

Paeonolum protects against MPP(+)-induced neurotoxicity in zebrafish and PC12 cells
por: Lu, Xi-Lin, et al.
Publicado: (2015)

The protective effect of sodium benzoate on aluminum toxicity in PC12 cell line
por: Arabsolghar, Rita, et al.
Publicado: (2017)

Protective Effect of Resveratrol Against Corticosterone-induced Neurotoxicity in PC12 Cells
por: Zhang, Ye, et al.
Publicado: (2019)

Astaxanthin Protects PC12 Cells against Homocysteine- and Glutamate-Induced Neurotoxicity
por: Chang, Chi-Huang, et al.
Publicado: (2020)

Mitogen-activated protein kinase phosphatase 1 protects PC12 cells from amyloid beta-induced neurotoxicity
por: Gu, Yue, et al.
Publicado: (2018)

Antidepressant Flavonoids and Their Relationship with Oxidative Stress
por: Hritcu, Lucian, et al.
Publicado: (2017)

Preparative Purification of Total Flavonoids from Sophora tonkinensis Gagnep. by Macroporous Resin Column Chromatography and Comparative Analysis of Flavonoid Profiles by HPLC-PAD
por: Hou, Mengyang, et al.
Publicado: (2019)

The dietary flavonoid isoliquiritigenin is a potent cytotoxin for human neuroblastoma cells
por: Alshangiti, Amnah M., et al.
Publicado: (2019)

Protective role of Clitoria ternatea L. flower extract on methylglyoxal-induced protein glycation and oxidative damage to DNA
por: Chayaratanasin, Poramin, et al.
Publicado: (2021)

Hyperglycemia Impairs Proteasome Function by Methylglyoxal
por: Queisser, Markus A., et al.
Publicado: (2010)

Methylglyoxal interaction with superoxide dismutase 1
por: Polykretis, Panagis, et al.
Publicado: (2020)

Arginine glycosylation enhances methylglyoxal detoxification
por: El Qaidi, Samir, et al.
Publicado: (2021)

The possible role of methylglyoxal metabolism in cancer
por: Alfarouk, Khalid O., et al.
Publicado: (2021)

Resveratrol Protects PC12 Cell against 6-OHDA Damage via CXCR4 Signaling Pathway
por: Zhang, Jing, et al.
Publicado: (2015)

Edaravone Protects against Methylglyoxal-Induced Barrier Damage in Human Brain Endothelial Cells
por: Tóth, Andrea E., et al.
Publicado: (2014)

Major anthocyanins in elderberry effectively trap methylglyoxal and reduce cytotoxicity of methylglyoxal in HepG2 cell line
por: Ferreira, Sandrine S., et al.
Publicado: (2022)

Protective Effects of Selol Against Sodium Nitroprusside-Induced Cell Death and Oxidative Stress in PC12 Cells
por: Dominiak, Agnieszka, et al.
Publicado: (2016)

Protective effects of nimodipine and lithium against aluminum-induced cell death and oxidative stress in PC12 cells
por: Saberzadeh, Jamileh, et al.
Publicado: (2016)

Berberine protects against glutamate-induced oxidative stress and apoptosis in PC12 and N2a cells
por: Sadeghnia, Hamid Reza, et al.
Publicado: (2017)

Erigeron annuus Protects PC12 Neuronal Cells from Oxidative Stress Induced by ROS-Mediated Apoptosis
por: Lee, Ji Yeon, et al.
Publicado: (2020)

Soybean Whey Bio-Processed Using Weissella hellenica D1501 Protects Neuronal PC12 Cells Against Oxidative Damage
por: Yin, Liqing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2vbrj345l1qkmi0i1kor7h448k